DisGeNET - a database of gene-disease associations

ETS1, ETS proto-oncogene 1, transcription factor, 2113

N. diseases: 327; N. variants: 20

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11221357

Entrez Id:	2113;105369565
Gene Symbol:	ETS1;LOC105369565

ETS1;LOC105369565

CUI:	C0200638
Disease:

Eosinophil count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs116502295

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0869220
Disease:

Adverse effects, not elsewhere classified

0.700

GeneticVariation

GWASCAT

Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records.

30420678

2019

dbSNP:

rs11819995

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.700

GeneticVariation

GWASCAT

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.

30718926

2019

dbSNP:

rs7108992

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0042834
Disease:

Vital capacity

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs8705

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0023508
Disease:

White Blood Cell Count procedure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs4937333

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0024141
Disease:

Lupus Erythematosus, Systemic

0.010

GeneticVariation

BEFREE

These findings suggest that the rs4937333 T allele is a risk factor for susceptibility to SLE in the studied population.

31275358

2019

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0040420
Disease:

Tonometry

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses identify new loci influencing intraocular pressure.

29617998

2018

dbSNP:

rs67232546

Entrez Id:	2113;101929517
Gene Symbol:	ETS1;ETS1-AS1

ETS1;ETS1-AS1

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.

30054458

2018

dbSNP:

rs7924522

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0017601
Disease:

Glaucoma

0.700

GeneticVariation

GWASCAT

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.

30054594

2018

dbSNP:

rs7924522

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0040420
Disease:

Tonometry

0.700

GeneticVariation

GWASCAT

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.

30054594

2018

dbSNP:

rs7924522

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0040420
Disease:

Tonometry

0.700

GeneticVariation

GWASCAT

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma.

29785010

2018

dbSNP:

rs7924522

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0040420
Disease:

Tonometry

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses identify new loci influencing intraocular pressure.

29617998

2018

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0021390
Disease:

Inflammatory Bowel Diseases

0.700

GeneticVariation

GWASCAT

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

28067908

2017

dbSNP:

rs7117932

Entrez Id:	2113;105369565
Gene Symbol:	ETS1;LOC105369565

ETS1;LOC105369565

CUI:	C0751356
Disease:

Idiopathic Inflammatory Myopathies

0.010

GeneticVariation

BEFREE

Our data indicated that the rs7117932 alleles and genotypes are associated with DM and IIMs (P c = 6.0 × 10-3 and P c = 0.029; P c = 0.013 and P c = 0.019, respectively).

29030598

2017

dbSNP:

rs7117932

Entrez Id:	2113;105369565
Gene Symbol:	ETS1;LOC105369565

ETS1;LOC105369565

CUI:	C0206062
Disease:

Lung Diseases, Interstitial

0.010

GeneticVariation

BEFREE

The percentages of rs7117932 and rs6590330 SNPs were significantly greater in DM and IIM patients with interstitial lung disease (ILD) (all P c < 0.05).

29030598

2017

dbSNP:

rs1128334

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0024141
Disease:

Lupus Erythematosus, Systemic

0.810

GeneticVariation

GWASCAT

Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

26663301

2016

dbSNP:

rs11221322

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0010346
Disease:

Crohn Disease

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221322

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0008313
Disease:

Cholangitis, Sclerosing

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221322

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0033860
Disease:

Psoriasis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221322

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0009324
Disease:

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221322

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0038013
Disease:

Ankylosing spondylitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0038013
Disease:

Ankylosing spondylitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0010346
Disease:

Crohn Disease

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0033860
Disease:

Psoriasis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016

dbSNP:

rs11221332

Entrez Id:	2113
Gene Symbol:	ETS1

ETS1

CUI:	C0009324
Disease:

Ulcerative Colitis

0.700

GeneticVariation

GWASCAT

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

26974007

2016